Hueng-Sik Choi Selected Research

Insulin (Novolin)

12/2014	PKB/Akt phosphorylation of ERRγ contributes to insulin-mediated inhibition of hepatic gluconeogenesis.
6/2014	B-cell translocation gene 2 regulates hepatic glucose homeostasis via induction of orphan nuclear receptor Nur77 in diabetic mouse model.
5/2013	Insulin directly regulates steroidogenesis via induction of the orphan nuclear receptor DAX-1 in testicular Leydig cells.
2/2013	Emodin regulates glucose utilization by activating AMP-activated protein kinase.

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Hueng-Sik Choi Research Topics

Disease

10	Inflammation (Inflammations) 01/2023 - 01/2013
8	Insulin Resistance 03/2016 - 08/2011
8	Type 2 Diabetes Mellitus (MODY) 03/2016 - 02/2008
7	Neoplasms (Cancer) 04/2020 - 05/2006
6	Infections 10/2022 - 07/2008
6	Fatty Liver 12/2019 - 09/2009
5	Hepatocellular Carcinoma (Hepatoma) 01/2023 - 04/2005
5	Alcoholic Liver Diseases (Alcoholic Liver Disease) 06/2021 - 07/2013
5	Fibrosis (Cirrhosis) 01/2020 - 09/2009
5	Dosage-sensitive sex reversal 05/2013 - 05/2004
4	Liver Cirrhosis (Hepatic Cirrhosis) 01/2023 - 03/2010
4	Obesity 01/2018 - 04/2009
4	Prostatic Neoplasms (Prostate Cancer) 11/2014 - 05/2006
4	Familial Hypoadrenocorticism 03/2010 - 05/2004
3	Non-alcoholic Fatty Liver Disease 01/2023 - 10/2011
3	Sepsis (Septicemia) 04/2020 - 07/2011
3	Hepatitis 01/2020 - 01/2018
3	Anaplastic Thyroid Carcinoma 01/2019 - 11/2016
3	Body Weight (Weight, Body) 01/2018 - 07/2004
3	Thrombosis (Thrombus) 01/2018 - 12/2009
3	Metabolic Syndrome (Dysmetabolic Syndrome X) 03/2016 - 04/2009
3	Vascular Calcification 01/2016 - 11/2015
3	Hypoxia (Hypoxemia) 04/2015 - 01/2012
2	Malnutrition (Nutritional Deficiencies) 10/2022 - 01/2018
2	Virus Diseases (Viral Diseases) 10/2022 - 01/2019
2	Liver Diseases (Liver Disease) 01/2020 - 01/2013
2	Acute Liver Failure (Fulminant Hepatic Failure) 01/2018 - 07/2015
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2018 - 01/2010
2	Stomach Neoplasms (Stomach Cancer) 01/2018 - 01/2018
2	Atherosclerosis 11/2015 - 07/2014
2	Necrosis 02/2015 - 05/2013
2	Cardiomegaly (Heart Hypertrophy) 08/2014 - 12/2013
2	Hyperlipidemias (Hyperlipidemia) 07/2014 - 09/2009
2	Hyperglycemia 09/2013 - 08/2013
2	Insulinoma 03/2012 - 02/2007
2	Hyperplasia 11/2010 - 12/2009
1	Biliary Atresia 01/2023
1	Pancreatitis 01/2023
1	Melanoma (Melanoma, Malignant) 12/2022
1	COVID-19 10/2022
1	RNA Virus Infections 10/2022
1	Cytokine Release Syndrome 10/2022

Drug/Important Bio-Agent (IBA)

14	Estrogens (Estrogen)FDA Link 01/2023 - 01/2012
12	Orphan Nuclear ReceptorsIBA 01/2021 - 05/2004
8	Glucose (Dextrose)FDA LinkGeneric 12/2014 - 08/2008
7	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 01/2023 - 08/2004
7	EnzymesIBA 12/2019 - 05/2013
7	Proteins (Proteins, Gene)FDA Link 11/2016 - 09/2009
6	GSK5182IBA 01/2023 - 01/2012
5	Metformin (Glucophage)FDA LinkGeneric 03/2016 - 02/2008
5	Co-Repressor ProteinsIBA 11/2014 - 05/2006
4	Bile Acids and Salts (Bile Acids)IBA 01/2023 - 01/2013
4	CytokinesIBA 10/2022 - 02/2015
4	Messenger RNA (mRNA)IBA 01/2015 - 09/2009
4	Insulin (Novolin)FDA Link 12/2014 - 02/2013
4	Plasminogen Activator Inhibitor 1IBA 03/2010 - 09/2009
3	Transcription Factors (Transcription Factor)IBA 01/2023 - 01/2014
3	Carrier Proteins (Binding Protein)IBA 06/2021 - 01/2014
3	IronIBA 06/2020 - 04/2014
3	HepcidinsIBA 06/2020 - 04/2014
3	ElementsIBA 01/2020 - 01/2014
3	Concanavalin AIBA 01/2020 - 01/2018
3	CannabinoidsIBA 11/2019 - 08/2011
3	sodium-iodide symporter (sodium iodide symporter)IBA 01/2019 - 11/2016
3	Therapeutic UsesIBA 01/2019 - 04/2009
3	Acetaminophen (Paracetamol)FDA LinkGeneric 01/2018 - 05/2013
3	AntioxidantsIBA 01/2017 - 11/2010
3	pyruvate dehydrogenase kinase 4IBA 01/2016 - 01/2012
3	Fenofibrate (CiL)FDA LinkGeneric 12/2015 - 09/2009
3	Androgen Receptors (Androgen Receptor)IBA 11/2014 - 05/2006
3	Hypoglycemic Agents (Hypoglycemics)IBA 08/2014 - 02/2008
3	Transforming Growth Factor beta (TGF-beta)IBA 03/2010 - 09/2009
3	Plasminogen InactivatorsIBA 03/2010 - 09/2009
2	Interleukin-6 (Interleukin 6)IBA 01/2023 - 06/2020
2	Chenodeoxycholic Acid (Chenix)FDA Link 01/2023 - 01/2015
2	Antiviral Agents (Antivirals)IBA 10/2022 - 01/2019
2	Protein Kinases (Protein Kinase)IBA 01/2018 - 02/2014
2	CholesterolIBA 01/2018 - 07/2014
2	Hormones (Hormone)IBA 01/2018 - 10/2012
2	Fibrinogen (Factor I)FDA Link 01/2018 - 01/2017
2	Cytochrome P-450 CYP2E1 (CYP2E1)IBA 02/2016 - 07/2013
2	AMP-Activated Protein KinasesIBA 12/2015 - 10/2012
2	EndotoxinsIBA 07/2015 - 07/2011
2	AndrogensIBA 11/2014 - 01/2008
2	Blood Glucose (Blood Sugar)IBA 06/2014 - 09/2013
2	NAD (NADH)IBA 02/2014 - 04/2009
2	Thioctic Acid (Lipoic Acid)IBA 11/2010 - 03/2010
2	Angiotensin IIIBA 01/2010 - 12/2009
2	DNA (Deoxyribonucleic Acid)IBA 05/2006 - 08/2004
1	Fibroblast Growth Factor-23IBA 01/2023
1	Microphthalmia-Associated Transcription FactorIBA 12/2022
1	Melanocyte-Stimulating Hormones (MSH)IBA 12/2022
1	Lipase (Acid Lipase)FDA Link 10/2022
1	LipidsIBA 10/2022
1	Membrane Transport Proteins (Biological Pump)IBA 10/2022
1	Viral RNAIBA 10/2022
1	Nonesterified Fatty Acids (NEFA)IBA 10/2022

Therapy/Procedure

7	Therapeutics 01/2023 - 04/2009
3	Ligation 01/2020 - 03/2010
2	Stents 11/2010 - 12/2009